Name  :    Fluconazole
Shape :    White powder

Use for : 

1. Candidiasis: for the treatment of oropharyngeal and esophageal candidiasis infections;Disseminated candidiasis, including peritonitis, pneumonia, urinary tract infections, such as candidiasis vulvovaginitis.It can also be used for bone marrow transplant patients to receive cytotoxic drugs or radiation therapy to prevent the occurrence of candida infection.

2. Cryptococcosis: for the treatment of cryptococcus neoformans outside the meninges;In the treatment of cryptococcal meningitis, this product can be used as a maintenance therapy after initial treatment of amphotericin B combined with fluorocytosine.

3. Coccidiomycosis.

4. It can also be used as a substitute for itraconazole in the treatment of blastomycosis and histoplasmosis.

      

      Fluorotriazole is a kind of antifungal agent. Its antibacterial spectrum is similar to ketoconazole, and its antibacterial activity is stronger than ketoconazole.The mechanism of action is inhibition of ergosterol synthase, a necessary component of fungal cell membrane, which hinders ergosterol synthesis, destroys the integrity of fungal cell wall, and inhibits its growth and reproduction.This product to candida albicans, the size of the spores bacteria, cryptococcus neoformans, epidermis tinea bacteria and capsulatum cytoplasmic bacteria have strong antibacterial activity.Good oral absorption, widely distributed in the body, can penetrate into the cerebrospinal fluid.Clinically, it is mainly used for vaginal candidiasis, thrush, attrophic oral candidiasis, fungal meningitis, pulmonary fungal infection, abdominal infection, urinary tract infection and skin fungal infection, etc.