Quick detail:
Product Name: SR9011
CAS: 1379686-29-9
MF: C23H31ClN4O3S
MW: 479.03524
Type: Analysis reagent
Grade: Medicine Grade
Standard: USP
Apprarance: White powder
Application:
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.
Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.
Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic.
MK677 Nutrobal Ibutamore,MK-2866 Ostarine,AICAR Acadesine:
LGD-4033 Ligandrol,Andarine S4,GW501516 Cardarine:
SR9009 Stenabolic,RAD140 Testolone,YK11:
S23,AC 262356,SR9011,GW-0742:
Product list:
Our advantages:
1. Top quality and factory price,a discount would be given when you make a large order.
2. Rich experienced in delivering,package will be reshipped if sent failed.
3. Enough SR9011 stock ensure the prompt delivery time.
4. Good after-sales service,any of your question would be solved for the first as soon as possible.
5. Adhering to the principle of customer first conviction,we will provide the best and the most sincere services as possible as we can.
Product Name: SR9011
CAS: 1379686-29-9
MF: C23H31ClN4O3S
MW: 479.03524
Type: Analysis reagent
Grade: Medicine Grade
Standard: USP
Apprarance: White powder
Application:
SR9011 is a potent and specific synthetic REV-ERB agonist that binds to REV-ERB-α with an EC50 ~790 nM and REV-ERB-β with EC50 ~560 nM. It also has good in vivo plasma/brain exposure. The nuclear receptors REV-ERB-α and REV-ERB-β play an integral role in regulating the expression of core clock proteins, driving rhythms in activity and metabolism.
Administration of SR9011 alters circadian behavior and the circadian pattern of core clock gene expression in the hypothalami of mice. The circadian expression pattern of an array of metabolic genes in the liver, skeletal muscle and adipose tissue was also altered, resulting in increased energy expenditure.
Treatment of diet-induced obese mice with SR9011 decreased obesity by reducing fat mass and markedly improved dyslipidaemia and hyperglycaemia. These results indicate that synthetic REV-ERB ligands that pharmacologically target the circadian rhythm may be beneficial in the treatment of sleep disorders as well as metabolic.
MK677 Nutrobal Ibutamore,MK-2866 Ostarine,AICAR Acadesine:
LGD-4033 Ligandrol,Andarine S4,GW501516 Cardarine:
SR9009 Stenabolic,RAD140 Testolone,YK11:
S23,AC 262356,SR9011,GW-0742:
Product list:
| Anabolics | TesCypionate TesEnanthate TesPropionate TesDecano TesAcetate | Sus250 TesPhenylpropionate TesIsocaproate TesUndecano TesBase |
| Oxan / Ana Oxy/ Anad | Metan / Dian Stan / wins | |
| TreAcetate TreEnanthate TreHexahydrobenzyl carbonate TreBase | DrosPropionate / MastPropionate DrosEnanthate / MastEnanthate MethAcetate / PrimAcetate MethEnanthate / PrimEnanthate | |
| Fluoxy/ Halot Mester/ Provi 17alpha-Methyl-1-tes Methyltes 17alpha-Methyl-Dro/ Super | 4-Chlorotescetate/ClostAcetate Epiandrost Dehydroepiandrost 7-Keto-dehydroepiandrost 4Chlorodehydromethyltes/oral turi | |
| NandDecan NandPhenylpropionate | Nand Base NandCypionate NandUndecylate | |
| BoldUndecano/ Equi BoldeAcetate | BoldBase BoldCypionate BoldPropionate | |
| Sild/via Dutasterid / Avodar Finasterid / Prosca | TadaCitrate / Cia Vard /Levi Dapo / Pril Yohimbine Hydrochloride / Corynine / Aphrodine | |
| Anti-Estrogen | TamoCitrate / Nolvx ClomCitrate / Clo Letr | Anas / Arim Exem/Arom T3 /Cytomel /Liothyronine sodium T4 /L-Thyroxine /tetraiodothyronine |
| GH &Peptides | GH CG GH raw powder MT2 raw powder Ghrp2 raw powder GHrp6 raw powder Cjc 1295 raw powder IFG-1(1-3) GF-1 LR3 GH fragment176-191 CJC-1295 CJG-1295DAC GHRP-6 GHRP-2 MGF | PEG-MGF Ipamorelin Sermorelin Gonadorelin Tesamorelin TB-500 Selank DISP PT-141 Melanotan1 Melanotan2 Epithalon Myostatin Follistatin ACE-031 HMG |
| Sarms | MK-677/Nutrobal / Ibutamore MK-2866 /Ostarine LGD-4033 /Anabolicum SR9009 GW 501516 /Cardarine S-4 /Andarine | S-23 RAD-140 YK-11 AICAR GW 0742 SR9011 AC262356 |
| Local Anaesthetic | Benzocaine Benzocain HCL Lidocaine Lidocaine HCL | Tetracaine Tetracaine HCL Procaine Procaine HCL |
| Weight loss | T3 / Liothyronine sodium T4 / L-Thyroxine GH | L (-) -Carnitine L-Carnitine-L-Tartrate SARMS |
Our advantages:
1. Top quality and factory price,a discount would be given when you make a large order.
2. Rich experienced in delivering,package will be reshipped if sent failed.
3. Enough SR9011 stock ensure the prompt delivery time.
4. Good after-sales service,any of your question would be solved for the first as soon as possible.
5. Adhering to the principle of customer first conviction,we will provide the best and the most sincere services as possible as we can.